This is a technical overview of an INVAMED device within the deep vein thrombosis (dvt) portfolio. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition.
Mantis CURVE Over-the-Wire (OTW) Rotational Pharmacomechanical Thrombectomy System: Overview
Over-the-wire rotational pharmacomechanical thrombectomy system combining mechanical clot disruption with local thrombolytic drug delivery for wire-guided treatment of venous thrombosis.
How It Works and Where It Fits
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Clotted arteriovenous fistulas and grafts used for dialysis access can sometimes be salvaged with mechanical thrombectomy. Mechanical thrombectomy uses a catheter-based device to physically break up and/or remove clot from the vein, restoring flow in a single session where feasible.
Key Considerations
- All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU.
- Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.
- Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
Frequently Asked Questions
What is the regulatory status of these devices?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Does thrombectomy replace blood thinners?
No. Catheter thrombectomy removes existing clot but is generally used alongside anticoagulation, not as a replacement; management is individualized.
Can thrombectomy be done in one session?
Mechanical thrombectomy is often designed to restore flow in a single session where feasible, but this depends on the clot and is judged by the operator.
Clinical and Technical Context
INVAMED's Mantis XP is positioned specifically for fistula thrombectomy. Use of any thrombolytic is governed by bleeding-risk assessment performed by the clinician. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. Device choice within a mechanical approach depends on clot location, chronicity, and vessel size. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family. All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. Large-bore aspiration requires appropriately sized access and attention to blood-loss management. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. Access salvage decisions are made by the vascular access team based on the specific circuit. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. CDT is typically reserved for selected patients after careful bleeding-risk evaluation. INVAMED's Viper ULTRA thrombolysis catheter is designed for this localized infusion role.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Mantis PRO Rotational Thrombectomy & Ultra Aspiration: What Clinicians and Buyers Should Know
- Mantis Directional Thrombectomy System — Technical Overview
- Inside the Dovi Thrombus Ultra Aspiration Catheter: Design and Applications
Important Disclaimer
This content is educational and technical in nature and must not be interpreted as medical advice or as a promise of any clinical outcome. Individual results depend on many factors and can only be evaluated by a treating physician. Figures attributed to INVAMED reflect manufacturer or published data and are not a guarantee of results. All INVAMED devices are to be used by trained clinicians per the approved IFU, and availability is subject to local regulatory status.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.