This is a technical overview of an INVAMED device within the deep vein thrombosis (dvt) portfolio. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism.
Mantis PRO Rotational Thrombectomy & Ultra Aspiration: Overview
Rotational thrombectomy system combining mechanical clot fragmentation with strong aspiration for deep venous or arterial occlusions. Its innovative rotating leaf-shaped tip provides superior clot engagement and breakdown, paired with pharmacomechanical capability; the flexible, responsive catheter navigates complex vascular structures and precision rotational control adapts to various clot consistencies and locations. For DVT, the Mantis platform offers three approaches: rotational clot disruption, high-vacuum aspiration, and pharmacomechanical thrombolysis combining mechanical action with drug delivery.
Technical Specifications
Specifications per INVAMED product documentation; confirm current details in the official IFU.
| Attribute | Detail |
|---|---|
| Catheter design | rotational wire with leaf-shaped tip and integrated aspiration lumen |
| Material | stainless steel or nitinol drive shaft with flexible polymer outer sheath; nitinol shaft reinforced with PA/PEBAX polymers for high torque at low profile |
| Specification | Rotational speed range ~40,000-80,000 rpm |
| Specification | authorized for the European market under the Medical Device Directive (the earlier European regulatory framework 93/42/EEC); manufactured in internationally recognized quality management standards certified facilities |
How It Works and Where It Fits
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Clotted arteriovenous fistulas and grafts used for dialysis access can sometimes be salvaged with mechanical thrombectomy. An inferior vena cava (IVC) filter is a device placed in the large abdominal vein to catch clot fragments before they can reach the lungs.
Key Considerations
- Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes.
- Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
- Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable.
Frequently Asked Questions
What is the Mantis platform?
Mantis is INVAMED's thrombectomy family, offering rotational (Mantis PRO, Mantis CURVE), aspiration (Mantis AspireJET, Dovi), and fistula-specific (Mantis XP) options.
What is the regulatory status of these devices?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Does thrombectomy replace blood thinners?
No. Catheter thrombectomy removes existing clot but is generally used alongside anticoagulation, not as a replacement; management is individualized.
About INVAMED
INVAMED operates a dedicated R&D center (INVAcenter) focused on minimally invasive device development. INVAMED is a medical device manufacturer headquartered in Ankara, Turkey, founded in 2005.
Clinical and Technical Context
Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. Use of any thrombolytic is governed by bleeding-risk assessment performed by the clinician. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Understanding Aspiration Thrombectomy
- Comparing Mechanical thrombectomy and Thrombolysis alone
- Deep Vein Thrombosis (DVT): A Complete Technical Guide
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.