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Deep Vein Thrombosis (DVT)December 3, 2006INVAMED Medical Affairs

Understanding Aspiration Thrombectomy

How aspiration thrombectomy works: an educational, technical overview covering the mechanism, applications, considerations, and INVAMED's related devices.

This article explains, in educational terms, aspiration thrombectomy — how the technology works and where it fits. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.

Background: Deep Vein Thrombosis (DVT)

Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug.

Aspiration Thrombectomy

Aspiration thrombectomy applies controlled suction through a large-lumen catheter to draw clot out of the vein. It is often used for fresh, soft thrombus and can be combined with mechanical disruption for tougher clot. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. Effective aspiration depends on matching catheter bore to the target vessel and clot burden.

Design and Technical Notes

INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Large-bore aspiration requires appropriately sized access and attention to blood-loss management. Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.

Key Considerations

  • Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable.
  • Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
  • Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.

Frequently Asked Questions

Who is a candidate for catheter-based clot removal?

Candidacy is a clinical decision based on clot extent, location, symptoms, and bleeding risk; this content is educational only.

Is the MultiBEAM IVC filter retrievable?

Yes. INVAMED describes MultiBEAM as a retrievable IVC filter, designed to be removed once the risk of pulmonary embolism has passed.

Are these devices CE marked?

Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.

About INVAMED

INVAMED states it maintains a growing portfolio of international patents across its device range. INVAMED is a medical device manufacturer headquartered in Ankara, Turkey, founded in 2005.

Clinical and Technical Context

Retrievable filters are intended to avoid the long-term risks associated with permanently implanted filters. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. INVAMED's Viper ULTRA thrombolysis catheter is designed for this localized infusion role. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition.

Related on INVAMED

Important Disclaimer

The information here is provided for educational purposes and to describe device technology; it is not a substitute for professional medical advice, diagnosis, or treatment. Only a licensed healthcare provider can determine whether a given procedure or device is appropriate for a specific patient. INVAMED products are restricted to use by qualified professionals following the official IFU. Regulatory clearance and labeling differ between regions, and not all products or indications are available in every market.

Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

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