This article compares two approaches side by side to clarify how they differ in principle and practice. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug.
Mechanical thrombectomy vs Thrombolysis alone: Key Differences
Mechanical thrombectomy removes clot directly with a device, while thrombolysis relies on a drug to dissolve it over hours. The mechanical route can restore flow faster and may reduce the amount of thrombolytic drug needed, lowering bleeding exposure. Thrombolysis alone avoids mechanical instrumentation but typically requires an infusion period and monitoring. Many modern strategies blend the two as pharmacomechanical therapy; the approach is chosen per patient.
How INVAMED Supports Both Approaches
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Catheter French sizes and working lengths are specified in product documentation; buyers should confirm local registration status. INVAMED positions the Mantis family as a modular thrombectomy platform covering rotational, aspiration, and pharmacomechanical mechanisms.
Key Considerations
- Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.
- All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU.
- Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician.
Frequently Asked Questions
Are these devices CE marked?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
What is the Mantis platform?
Mantis is INVAMED's thrombectomy family, offering rotational (Mantis PRO, Mantis CURVE), aspiration (Mantis AspireJET, Dovi), and fistula-specific (Mantis XP) options.
Can thrombectomy be done in one session?
Mechanical thrombectomy is often designed to restore flow in a single session where feasible, but this depends on the clot and is judged by the operator.
About INVAMED
INVAMED operates a dedicated R&D center (INVAcenter) focused on minimally invasive device development. INVAMED is a medical device manufacturer headquartered in Ankara, Turkey, founded in 2005.
Clinical and Technical Context
Effective aspiration depends on matching catheter bore to the target vessel and clot burden. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Retrievable filters are intended to avoid the long-term risks associated with permanently implanted filters. INVAMED's Mantis PRO combines rotational clot disruption with ultra-aspiration in one platform, according to the company. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable. Large-bore aspiration requires appropriately sized access and attention to blood-loss management. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family. All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Mantis PRO Rotational Thrombectomy & Ultra Aspiration: What Clinicians and Buyers Should Know
- Thrombectomy vs Anticoagulation for DVT: What Is the Difference?
- Thrombectomy for Dialysis Fistula: How It Works and Why It Matters
Important Disclaimer
The information here is provided for educational purposes and to describe device technology; it is not a substitute for professional medical advice, diagnosis, or treatment. Only a licensed healthcare provider can determine whether a given procedure or device is appropriate for a specific patient. INVAMED products are restricted to use by qualified professionals following the official IFU. Regulatory clearance and labeling differ between regions, and not all products or indications are available in every market.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.