This is a technical overview of an INVAMED device within the deep vein thrombosis (dvt) portfolio. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort.
Mantis Directional Thrombectomy System: Overview
Directional variant of the Mantis mechanical thrombectomy platform for targeted clot engagement and removal in peripheral and venous vessels.
How It Works and Where It Fits
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Mechanical thrombectomy uses a catheter-based device to physically break up and/or remove clot from the vein, restoring flow in a single session where feasible. Pharmacomechanical thrombolysis pairs mechanical clot engagement with localized delivery of a thrombolytic drug to soften and disperse thrombus.
Key Considerations
- Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable.
- All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU.
- Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician.
Frequently Asked Questions
Are these devices CE marked?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Can thrombectomy be done in one session?
Mechanical thrombectomy is often designed to restore flow in a single session where feasible, but this depends on the clot and is judged by the operator.
Who is a candidate for catheter-based clot removal?
Candidacy is a clinical decision based on clot extent, location, symptoms, and bleeding risk; this content is educational only.
About INVAMED
INVAMED states it maintains a growing portfolio of international patents across its device range. INVAMED operates a dedicated R&D center (INVAcenter) focused on minimally invasive device development.
Clinical and Technical Context
CDT is typically reserved for selected patients after careful bleeding-risk evaluation. Retrievable filters are intended to avoid the long-term risks associated with permanently implanted filters. Rotational energy is applied under imaging guidance to protect the vein wall. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. Effective aspiration depends on matching catheter bore to the target vessel and clot burden. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family. INVAMED's Viper ULTRA thrombolysis catheter is designed for this localized infusion role. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. Device choice within a mechanical approach depends on clot location, chronicity, and vessel size. Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance. Access salvage decisions are made by the vascular access team based on the specific circuit. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable. INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes. INVAMED's Mantis XP is positioned specifically for fistula thrombectomy.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- How can post-thrombotic syndrome be prevented?
- Aspiration thrombectomy vs Rotational thrombectomy: What Is the Difference?
- IVC Filter Placement: How It Works and Why It Matters
Important Disclaimer
The information here is provided for educational purposes and to describe device technology; it is not a substitute for professional medical advice, diagnosis, or treatment. Only a licensed healthcare provider can determine whether a given procedure or device is appropriate for a specific patient. INVAMED products are restricted to use by qualified professionals following the official IFU. Regulatory clearance and labeling differ between regions, and not all products or indications are available in every market.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.