This article compares two approaches side by side to clarify how they differ in principle and practice. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism.
Aspiration thrombectomy vs Rotational thrombectomy: Key Differences
Aspiration removes clot by suction and works best on fresh, soft thrombus, while rotational thrombectomy macerates firmer, more organized clot. In practice the two mechanisms are complementary and are sometimes combined in a single device. INVAMED's Mantis platform offers both aspiration- and rotation-based options. Selecting a mechanism depends on how old and adherent the clot is.
How INVAMED Supports Both Approaches
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. The venous portfolio also includes the Viper ULTRA infusion catheter and the retrievable MultiBEAM IVC filter. Catheter French sizes and working lengths are specified in product documentation; buyers should confirm local registration status.
Key Considerations
- Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician.
- Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.
- Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes.
Frequently Asked Questions
Is the MultiBEAM IVC filter retrievable?
Yes. INVAMED describes MultiBEAM as a retrievable IVC filter, designed to be removed once the risk of pulmonary embolism has passed.
Can thrombectomy be done in one session?
Mechanical thrombectomy is often designed to restore flow in a single session where feasible, but this depends on the clot and is judged by the operator.
What is the Mantis platform?
Mantis is INVAMED's thrombectomy family, offering rotational (Mantis PRO, Mantis CURVE), aspiration (Mantis AspireJET, Dovi), and fistula-specific (Mantis XP) options.
About INVAMED
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Clinical and Technical Context
Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable. Effective aspiration depends on matching catheter bore to the target vessel and clot burden. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. CDT is typically reserved for selected patients after careful bleeding-risk evaluation. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes. INVAMED's Mantis PRO combines rotational clot disruption with ultra-aspiration in one platform, according to the company. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Large-bore aspiration requires appropriately sized access and attention to blood-loss management. Retrievable filters are intended to avoid the long-term risks associated with permanently implanted filters. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Deep Vein Thrombosis (DVT): A Complete Technical Guide
- Comparing Mechanical thrombectomy and Thrombolysis alone
- How is a blood clot removed from the leg?
Important Disclaimer
This content is educational and technical in nature and must not be interpreted as medical advice or as a promise of any clinical outcome. Individual results depend on many factors and can only be evaluated by a treating physician. Figures attributed to INVAMED reflect manufacturer or published data and are not a guarantee of results. All INVAMED devices are to be used by trained clinicians per the approved IFU, and availability is subject to local regulatory status.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.