This is a technical overview of an INVAMED device within the deep vein thrombosis (dvt) portfolio. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort.
Dovi Thrombus Ultra Aspiration Catheter: Overview
Large-lumen aspiration catheter for vacuum aspiration thrombectomy of venous thrombus.
How It Works and Where It Fits
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Rotational thrombectomy uses a rotating element to macerate organized or wall-adherent clot so it can be aspirated. An inferior vena cava (IVC) filter is a device placed in the large abdominal vein to catch clot fragments before they can reach the lungs.
Key Considerations
- All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU.
- Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
- Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.
Frequently Asked Questions
Who is a candidate for catheter-based clot removal?
Candidacy is a clinical decision based on clot extent, location, symptoms, and bleeding risk; this content is educational only.
Is the MultiBEAM IVC filter retrievable?
Yes. INVAMED describes MultiBEAM as a retrievable IVC filter, designed to be removed once the risk of pulmonary embolism has passed.
Can thrombectomy be done in one session?
Mechanical thrombectomy is often designed to restore flow in a single session where feasible, but this depends on the clot and is judged by the operator.
About INVAMED
INVAMED is a medical device manufacturer headquartered in Ankara, Turkey, founded in 2005. INVAMED operates a dedicated R&D center (INVAcenter) focused on minimally invasive device development.
Clinical and Technical Context
Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. INVAMED's Mantis PRO combines rotational clot disruption with ultra-aspiration in one platform, according to the company. Effective aspiration depends on matching catheter bore to the target vessel and clot burden. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. Access salvage decisions are made by the vascular access team based on the specific circuit. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. Retrievable filters are intended to avoid the long-term risks associated with permanently implanted filters. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family. Rotational energy is applied under imaging guidance to protect the vein wall. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Viper ULTRA Thrombolysis Catheter — Technical Overview
- Aspiration thrombectomy vs Rotational thrombectomy: What Is the Difference?
- Mechanical Thrombectomy: Technology, Uses and Considerations
Important Disclaimer
The information here is provided for educational purposes and to describe device technology; it is not a substitute for professional medical advice, diagnosis, or treatment. Only a licensed healthcare provider can determine whether a given procedure or device is appropriate for a specific patient. INVAMED products are restricted to use by qualified professionals following the official IFU. Regulatory clearance and labeling differ between regions, and not all products or indications are available in every market.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.