This article explains, in educational terms, mechanical thrombectomy — how the technology works and where it fits. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism.
Mechanical Thrombectomy
Mechanical thrombectomy uses a catheter-based device to physically break up and/or remove clot from the vein, restoring flow in a single session where feasible. By debulking thrombus directly, it can reduce reliance on prolonged clot-dissolving drug infusions and the bleeding risk those carry. INVAMED's Mantis PRO combines rotational clot disruption with ultra-aspiration in one platform, according to the company. Device choice within a mechanical approach depends on clot location, chronicity, and vessel size.
Design and Technical Notes
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes.
Key Considerations
- Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
- Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable.
- Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.
Frequently Asked Questions
What is the Mantis platform?
Mantis is INVAMED's thrombectomy family, offering rotational (Mantis PRO, Mantis CURVE), aspiration (Mantis AspireJET, Dovi), and fistula-specific (Mantis XP) options.
Is the MultiBEAM IVC filter retrievable?
Yes. INVAMED describes MultiBEAM as a retrievable IVC filter, designed to be removed once the risk of pulmonary embolism has passed.
Are these devices CE marked?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
About INVAMED
INVAMED operates a dedicated R&D center (INVAcenter) focused on minimally invasive device development. INVAMED states it holds more than 100 international patents across its device portfolio.
Clinical and Technical Context
Large-bore aspiration requires appropriately sized access and attention to blood-loss management. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable. Use of any thrombolytic is governed by bleeding-risk assessment performed by the clinician. CDT is typically reserved for selected patients after careful bleeding-risk evaluation. INVAMED's Mantis PRO combines rotational clot disruption with ultra-aspiration in one platform, according to the company. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes. Rotational energy is applied under imaging guidance to protect the vein wall.
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.