This is a technical overview of an INVAMED device within the deep vein thrombosis (dvt) portfolio. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome.
Mantis AspireJET Thrombectomy System: Overview
Aspiration-focused member of the Mantis thrombectomy family for high-vacuum clot aspiration in venous thromboembolism.
How It Works and Where It Fits
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Mechanical thrombectomy uses a catheter-based device to physically break up and/or remove clot from the vein, restoring flow in a single session where feasible. Pharmacomechanical thrombolysis pairs mechanical clot engagement with localized delivery of a thrombolytic drug to soften and disperse thrombus.
Key Considerations
- Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.
- Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician.
- Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes.
Frequently Asked Questions
Does thrombectomy replace blood thinners?
No. Catheter thrombectomy removes existing clot but is generally used alongside anticoagulation, not as a replacement; management is individualized.
Is the MultiBEAM IVC filter retrievable?
Yes. INVAMED describes MultiBEAM as a retrievable IVC filter, designed to be removed once the risk of pulmonary embolism has passed.
What is the Mantis platform?
Mantis is INVAMED's thrombectomy family, offering rotational (Mantis PRO, Mantis CURVE), aspiration (Mantis AspireJET, Dovi), and fistula-specific (Mantis XP) options.
About INVAMED
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Clinical and Technical Context
INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Device choice within a mechanical approach depends on clot location, chronicity, and vessel size. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. CDT is typically reserved for selected patients after careful bleeding-risk evaluation. INVAMED's Mantis XP is positioned specifically for fistula thrombectomy. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family. Retrievable filters are intended to avoid the long-term risks associated with permanently implanted filters. Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. Access salvage decisions are made by the vascular access team based on the specific circuit. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Can DVT be treated without blood thinners?
- Mantis PRO Rotational Thrombectomy & Ultra Aspiration: What Clinicians and Buyers Should Know
- Mantis CURVE Over-the-Wire (OTW) Rotational Pharmacomechanical Thrombectomy System — Technical Overview
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.