This article explains, in educational terms, rotational thrombectomy — how the technology works and where it fits. Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Whether an interventional approach is appropriate is a clinical decision that weighs clot age, location, bleeding risk, and overall condition. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism.
Rotational Thrombectomy
Rotational thrombectomy uses a rotating element to macerate organized or wall-adherent clot so it can be aspirated. This mechanism is useful when thrombus is more chronic and less responsive to suction alone. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family. Rotational energy is applied under imaging guidance to protect the vein wall.
Design and Technical Notes
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable.
Key Considerations
- Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes.
- Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician.
- Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
Frequently Asked Questions
What is the Mantis platform?
Mantis is INVAMED's thrombectomy family, offering rotational (Mantis PRO, Mantis CURVE), aspiration (Mantis AspireJET, Dovi), and fistula-specific (Mantis XP) options.
Can thrombectomy be done in one session?
Mechanical thrombectomy is often designed to restore flow in a single session where feasible, but this depends on the clot and is judged by the operator.
Does thrombectomy replace blood thinners?
No. Catheter thrombectomy removes existing clot but is generally used alongside anticoagulation, not as a replacement; management is individualized.
About INVAMED
INVAMED states it holds more than 100 international patents across its device portfolio. INVAMED is a medical device manufacturer headquartered in Ankara, Turkey, founded in 2005.
Clinical and Technical Context
Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. Access salvage decisions are made by the vascular access team based on the specific circuit. Use of any thrombolytic is governed by bleeding-risk assessment performed by the clinician. INVAMED's Viper ULTRA thrombolysis catheter is designed for this localized infusion role. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes. CDT is typically reserved for selected patients after careful bleeding-risk evaluation. Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician. Retrievable filters are intended to avoid the long-term risks associated with permanently implanted filters. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. Rotational energy is applied under imaging guidance to protect the vein wall. Large-bore aspiration requires appropriately sized access and attention to blood-loss management. Device choice within a mechanical approach depends on clot location, chronicity, and vessel size. Effective aspiration depends on matching catheter bore to the target vessel and clot burden. INVAMED's Mantis XP is positioned specifically for fistula thrombectomy. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Retrievable IVC filter vs Permanent IVC filter: What Is the Difference?
- Pharmacomechanical Thrombolysis Explained — A Technical Guide
- Viper ULTRA Thrombolysis Catheter — Technical Overview
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.