This is a technical overview of an INVAMED device within the deep vein thrombosis (dvt) portfolio. Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Left untreated, extensive iliofemoral DVT is associated with a higher risk of long-term complications such as post-thrombotic syndrome, marked by chronic swelling and discomfort. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug.
Mantis XP Thrombectomy System for Fistula: Overview
Mantis thrombectomy variant purpose-built for declotting thrombosed dialysis access fistulas and grafts.
How It Works and Where It Fits
INVAMED's Mantis platform is organized by the mechanism used to engage and remove venous clot, alongside protective and access tools. Clotted arteriovenous fistulas and grafts used for dialysis access can sometimes be salvaged with mechanical thrombectomy. An inferior vena cava (IVC) filter is a device placed in the large abdominal vein to catch clot fragments before they can reach the lungs.
Key Considerations
- Any use of thrombolytic drugs demands careful bleeding-risk assessment by the clinician.
- Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance.
- Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
Frequently Asked Questions
What is the regulatory status of these devices?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
What is the Mantis platform?
Mantis is INVAMED's thrombectomy family, offering rotational (Mantis PRO, Mantis CURVE), aspiration (Mantis AspireJET, Dovi), and fistula-specific (Mantis XP) options.
Does thrombectomy replace blood thinners?
No. Catheter thrombectomy removes existing clot but is generally used alongside anticoagulation, not as a replacement; management is individualized.
Clinical and Technical Context
Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance. Device choice within a mechanical approach depends on clot location, chronicity, and vessel size. All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU. INVAMED's Mantis AspireJET and Dovi ultra-aspiration catheter are positioned for high-vacuum clot removal. INVAMED's Mantis PRO and Mantis CURVE incorporate rotational action within the Mantis family. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Clot age and location strongly influence which mechanism — aspiration, rotation, or pharmacomechanical — is most suitable. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. Deep vein thrombosis is the formation of a blood clot within the deep veins, most often in the legs, and it can cause pain, swelling, and — if a fragment travels to the lungs — pulmonary embolism. Rotational energy is applied under imaging guidance to protect the vein wall. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. INVAMED's Mantis XP is positioned specifically for fistula thrombectomy. Use of any thrombolytic is governed by bleeding-risk assessment performed by the clinician. CDT is typically reserved for selected patients after careful bleeding-risk evaluation. INVAMED's MultiBEAM is a retrievable IVC filter, meaning it is designed to be removed once the risk period passes.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- How can post-thrombotic syndrome be prevented?
- MultiBEAM Inferior Vena Cava (IVC) Filter — Technical Overview
- Mantis PRO Rotational Thrombectomy & Ultra Aspiration: What Clinicians and Buyers Should Know
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.