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Neurovascular InterventionsAugust 15, 2024INVAMED Medical Affairs

What is the time window for stroke thrombectomy?

What is the time window for stroke thrombectomy? An educational, technical answer with device context from INVAMED. Informational only — not medical…

Below is an educational, technical answer to a question many patients and clinicians ask. Aneurysm techniques include packing the sac with detachable coils and redirecting flow across the neck with a densely braided flow diverter so the sac thromboses over time. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.

Background: Acute Ischemic Stroke and Intracranial Aneurysm Intervention

Intracranial aneurysms are focal outpouchings of a brain artery wall, and endovascular options aim to seal the aneurysm from circulation to reduce rupture risk. Acute ischemic stroke from a large vessel occlusion happens when a clot blocks a major brain artery, cutting off blood flow to a region of brain tissue. Because brain tissue is highly time-sensitive, rapid restoration of flow is central to endovascular stroke care in eligible patients.

What is the time window for stroke thrombectomy?

Thrombectomy has historically been described within an early window of roughly 6 hours, with extended selection out to about 24 hours in appropriately imaged patients. Eligibility in the extended window generally depends on advanced imaging showing salvageable brain tissue. According to INVAMED, its KinG device is described as capturing cerebral artery clots within a treatment window of up to 24 hours. The actual window and eligibility for an individual patient are determined by the stroke team using current criteria.

What This Means in Practice

Liquid embolic use requires attention to concentration, radiopacity, and injection control for the target lesion. Clot characteristics and vessel tortuosity influence whether a stent retriever, aspiration, or combined technique is chosen. For aneurysms, coil sizing and packing or flow-diverter selection are matched to the aneurysm's shape and neck.

Key Considerations

  • Speed to reperfusion is a central factor in stroke thrombectomy, which shapes device readiness and workflow in eligible patients.
  • Manufacturer statements, including the described up-to-24-hour window for the KinG device, reflect product content and do not establish individual eligibility.
  • All INVAMED neurovascular devices are intended for use by trained neurointerventional operators under imaging guidance and per the IFU.

Frequently Asked Questions

What are Spider coils made of?

According to INVAMED, Spider Intracranial Coils are made of a platinum-tungsten 92/8 percent alloy and are offered across 2 to 30 mm coil diameters in detachable and pushable configurations.

Who determines eligibility for thrombectomy?

The treating stroke team determines eligibility using imaging and current criteria; this article is educational and not medical advice.

What treatment window does INVAMED cite for the KinG device?

According to INVAMED product content, the KinG device is described as capturing and extracting cerebral artery clots within a treatment window of up to 24 hours; eligibility is a clinical determination.

About INVAMED

Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.

Clinical and Technical Context

INVAMED's Spider Intracranial Coil System uses a platinum-tungsten 92/8 percent alloy in detachable and pushable configurations with instant mechanical detachment; according to INVAMED, Spider coils provide aneurysm packing across 2 to 30 mm coil diameters. INVAMED's KinG Intracranial Revascularization Device is a self-expanding nitinol stent retriever with platinum markers at the proximal and distal ends of the basket for fluoroscopic visualization, intended for vessels including the internal carotid, middle and anterior cerebral, and basilar and vertebral arteries. INVAMED's Mantis Directional Thrombectomy System and AngioHAND Thrombus Removal System are positioned for aspiration-based clot removal in this setting. Aneurysm techniques include packing the sac with detachable coils and redirecting flow across the neck with a densely braided flow diverter so the sac thromboses over time.

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Important Disclaimer

This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.

Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

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