Below is an educational, technical answer to a question many patients and clinicians ask. Because brain tissue is highly time-sensitive, rapid restoration of flow is central to endovascular stroke care in eligible patients. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Acute Ischemic Stroke and Intracranial Aneurysm Intervention
Acute ischemic stroke from a large vessel occlusion happens when a clot blocks a major brain artery, cutting off blood flow to a region of brain tissue. Aneurysm techniques include packing the sac with detachable coils and redirecting flow across the neck with a densely braided flow diverter so the sac thromboses over time. Patient eligibility, the treatment window, and device selection are all determined by the treating neurointerventional team using imaging and current criteria.
What is the first-pass effect in thrombectomy?
First-pass effect refers to achieving complete or near-complete reperfusion with a single device pass, without needing additional attempts. It is used as a marker of an efficient procedure and has been associated with favorable outcomes in the literature. Achieving it depends on clot characteristics, technique, and device performance. The number of passes required is determined during the procedure by the operator.
What This Means in Practice
Clot characteristics and vessel tortuosity influence whether a stent retriever, aspiration, or combined technique is chosen. Liquid embolic use requires attention to concentration, radiopacity, and injection control for the target lesion. For aneurysms, coil sizing and packing or flow-diverter selection are matched to the aneurysm's shape and neck.
Key Considerations
- For aneurysms, coil sizing and packing or flow-diverter selection are matched to the aneurysm's shape and neck.
- Speed to reperfusion is a central factor in stroke thrombectomy, which shapes device readiness and workflow in eligible patients.
- All INVAMED neurovascular devices are intended for use by trained neurointerventional operators under imaging guidance and per the IFU.
Frequently Asked Questions
Are these neurovascular devices CE marked?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
What are Spider coils made of?
According to INVAMED, Spider Intracranial Coils are made of a platinum-tungsten 92/8 percent alloy and are offered across 2 to 30 mm coil diameters in detachable and pushable configurations.
What is the INVAMED stent retriever called?
INVAMED's stent retriever is the KinG Intracranial Revascularization Device, a self-expanding nitinol device with platinum markers for fluoroscopic visualization.
Clinical and Technical Context
Coil sizing and packing strategy are determined by the neurointerventionalist for the specific aneurysm. Manufacturer statements, including the described up-to-24-hour window for the KinG device, reflect product content and do not establish individual eligibility. Aneurysm techniques include packing the sac with detachable coils and redirecting flow across the neck with a densely braided flow diverter so the sac thromboses over time. The choice of aspiration, a stent retriever, or a combined approach is made by the operator based on clot and vessel characteristics. INVAMED's Mantis Directional Thrombectomy System and AngioHAND Thrombus Removal System are positioned for aspiration-based clot removal in this setting. According to INVAMED product content surfaced via its search index, the KinG device captures and extracts cerebral artery clots within a treatment window of up to 24 hours, though eligibility for any given patient is a clinical determination. Whether a flow diverter is appropriate, versus coiling, is a specialized decision made by the treating clinician. INVAMED's KinG Intracranial Revascularization Device is a self-expanding nitinol stent retriever with platinum markers at the proximal and distal ends of the basket for fluoroscopic visualization, intended for vessels including the internal carotid, middle and anterior cerebral, and basilar and vertebral arteries.
Related on INVAMED
- Neurovascular Interventions — product category
- Sourcing Neurovascular Interventions Devices: A Manufacturer and Procurement Guide
- InWIRE Neurovascular Guidewire — Technical Overview
- How does a stent retriever work?
Important Disclaimer
This content is educational and technical in nature and must not be interpreted as medical advice or as a promise of any clinical outcome. Individual results depend on many factors and can only be evaluated by a treating physician. Figures attributed to INVAMED reflect manufacturer or published data and are not a guarantee of results. All INVAMED devices are to be used by trained clinicians per the approved IFU, and availability is subject to local regulatory status.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.