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Neurovascular InterventionsSeptember 14, 2023INVAMED Medical Affairs

InWIRE Neurovascular Guidewire — Technical Overview

InWIRE Neurovascular Guidewire from INVAMED: an educational technical overview of its design, specifications, and clinical role in neurovascular…

This is a technical overview of an INVAMED device within the neurovascular interventions portfolio. Aneurysm techniques include packing the sac with detachable coils and redirecting flow across the neck with a densely braided flow diverter so the sac thromboses over time. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.

Background: Acute Ischemic Stroke and Intracranial Aneurysm Intervention

Mechanical thrombectomy removes the clot with a catheter-based device, and it is used in selected patients alongside or after intravenous thrombolysis where indicated. Aneurysm techniques include packing the sac with detachable coils and redirecting flow across the neck with a densely braided flow diverter so the sac thromboses over time. Intracranial aneurysms are focal outpouchings of a brain artery wall, and endovascular options aim to seal the aneurysm from circulation to reduce rupture risk.

InWIRE Neurovascular Guidewire: Overview

Neurovascular guidewire listed on invamed.com as an INVAMED Research & Development product (page title only; no further detail captured). The category meta description confirms neurovascular guidewires are part of the portfolio.

How It Works and Where It Fits

INVAMED's neurovascular portfolio spans clot retrieval, aspiration, aneurysm packing, embolization, and the access tools that reach the intracranial circulation. Reaching intracranial targets requires navigable microcatheters, distal access catheters, and neurovascular guidewires that track through tortuous cerebral vessels. Mechanical thrombectomy encompasses the catheter-based techniques used to physically remove a clot from a blocked cerebral artery.

Key Considerations

  • Clot characteristics and vessel tortuosity influence whether a stent retriever, aspiration, or combined technique is chosen.
  • Liquid embolic use requires attention to concentration, radiopacity, and injection control for the target lesion.
  • Manufacturer statements, including the described up-to-24-hour window for the KinG device, reflect product content and do not establish individual eligibility.

Frequently Asked Questions

Are these neurovascular devices CE marked?

Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.

What is the INVAMED stent retriever called?

INVAMED's stent retriever is the KinG Intracranial Revascularization Device, a self-expanding nitinol device with platinum markers for fluoroscopic visualization.

What is the Libro embolization agent?

INVAMED's Libro is a non-adhesive liquid embolic agent combining EVOH copolymer, DMSO solvent, and tantalum for radiopacity, offered per INVAMED in multiple viscosity formulas for AVMs and tumors.

Clinical and Technical Context

All INVAMED neurovascular devices are intended for use by trained neurointerventional operators under imaging guidance and per the IFU. Speed to reperfusion is a central factor in stroke thrombectomy, which shapes device readiness and workflow in eligible patients. Mechanical thrombectomy removes the clot with a catheter-based device, and it is used in selected patients alongside or after intravenous thrombolysis where indicated. According to INVAMED product content surfaced via its search index, the KinG device captures and extracts cerebral artery clots within a treatment window of up to 24 hours, though eligibility for any given patient is a clinical determination. INVAMED's Libro Non-Adhesive Embolization Agent combines EVOH copolymer, DMSO solvent, and tantalum powder for radiopacity, and per INVAMED is offered in multiple viscosity formulas, including 6 and 8 percent concentrations, for cerebral AVMs and tumors. Agent concentration and injection technique are selected by the operator for the target lesion. Liquid embolic use requires attention to concentration, radiopacity, and injection control for the target lesion. Access-device selection is made by the operator according to the vascular pathway and the therapy being delivered.

Related on INVAMED

Important Disclaimer

This content is educational and technical in nature and must not be interpreted as medical advice or as a promise of any clinical outcome. Individual results depend on many factors and can only be evaluated by a treating physician. Figures attributed to INVAMED reflect manufacturer or published data and are not a guarantee of results. All INVAMED devices are to be used by trained clinicians per the approved IFU, and availability is subject to local regulatory status.

Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

InWIRE Neurovascular Guidewiremechanical thrombectomy strokestent retrieverstroke clot retrieval proceduretime windowsuccess raterecanalization rate (TICI)
InWIRE Neurovascular Guidewire — Technical Overview | INVAMED