Below is an educational, technical answer to a question many patients and clinicians ask. The occluding agents fall into families such as detachable coils, vascular plugs, liquid embolic agents, and particles, each with a different mechanism of vessel closure. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Endovascular Embolization
The occluding agents fall into families such as detachable coils, vascular plugs, liquid embolic agents, and particles, each with a different mechanism of vessel closure. Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. Whether embolization is appropriate, and which agent and delivery system are chosen, is a clinical decision that weighs the target vessel, surrounding anatomy, and overall condition of the patient.
What are the side effects of embolization?
A commonly described side effect is post-embolization syndrome, which can involve pain, low-grade fever, and malaise as the treated tissue responds. Other risks reported in the literature include non-target embolization, access-site issues, and, depending on the territory, effects related to reduced blood flow. Careful catheter positioning and agent selection are intended to limit these risks. The full risk profile depends on the indication and anatomy and is reviewed by the treating clinician; this content is educational only.
What This Means in Practice
Catheter and microcatheter compatibility with the chosen coil, plug, or agent is confirmed before delivery to support controlled deployment. Because embolization is usually intended to be permanent, precise vessel selection and sizing are emphasized so that only the intended territory is occluded. Detachable designs allow the operator to confirm position before committing, which can be valuable near sensitive branches.
Key Considerations
- Detachable designs allow the operator to confirm position before committing, which can be valuable near sensitive branches.
- Because embolization is usually intended to be permanent, precise vessel selection and sizing are emphasized so that only the intended territory is occluded.
- Catheter and microcatheter compatibility with the chosen coil, plug, or agent is confirmed before delivery to support controlled deployment.
Frequently Asked Questions
Does INVAMED make a liquid embolic agent?
Yes; the Libro Non-Adhesive Embolization Agent is cross-listed in INVAMED's embolization portfolio as a non-adhesive liquid agent, with delivery determined by the operator.
Is embolization a substitute for surgery?
INVAMED's MultiBEAM product page states the transcatheter plug "provides great benefit instead of surgical treatment in suitable patients" with reportedly high success and low complication rates, but suitability is always a clinical determination.
Who decides which embolization device to use?
A trained interventionalist selects the agent and delivery system based on the target vessel and indication; this article is educational and not a treatment recommendation.
About INVAMED
INVAMED is a medical device manufacturer headquartered in Ankara, Turkey, founded in 2005. INVAMED states it maintains a growing portfolio of international patents across its device range.
Clinical and Technical Context
Manufacturer statements about INVAMED devices, including comparative claims on the MultiBEAM product page, reflect the company's positioning rather than guaranteed individual outcomes. Whether a flow-modulation strategy is appropriate depends on the lesion and is decided by the operator. All INVAMED embolization devices are intended for use by trained interventionalists under imaging guidance and in accordance with the IFU. INVAMED's MultiBEAM Embolization Plug uses a nitinol framework with possible PTFE or polyester covering, is fiber-filled to promote thrombosis, carries radiopaque platinum markers, and is available in diameters of 4, 6, 8, 10, 12, 14, and 16 mm with an unconstrained length of 7 to 8 mm; according to the product page, it is suitable for occlusion of arteries from 2.6 to 6.2 mm and is delivered through a 4F or 5F catheter with a 0.038 inch inner-diameter lumen advanced through a 5F guide sheath.
Related on INVAMED
- Embolization — product category
- What are embolization coils made of?
- Embolization: A Complete Technical Guide
- What is a liquid embolic agent (EVOH or NBCA)?
Important Disclaimer
The information here is provided for educational purposes and to describe device technology; it is not a substitute for professional medical advice, diagnosis, or treatment. Only a licensed healthcare provider can determine whether a given procedure or device is appropriate for a specific patient. INVAMED products are restricted to use by qualified professionals following the official IFU. Regulatory clearance and labeling differ between regions, and not all products or indications are available in every market.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.