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HomeINVAblogUnderstanding Transarterial and Targeted Embolization
EmbolizationMay 8, 2024INVAMED Medical Affairs

Understanding Transarterial and Targeted Embolization

How transarterial embolization works: an educational, technical overview covering the mechanism, applications, considerations, and INVAMED's related…

This article explains, in educational terms, transarterial embolization — how the technology works and where it fits. Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.

Background: Endovascular Embolization

Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. Transarterial approaches also include transarterial radioembolization (TARE) and other targeted therapies delivered through dedicated microcatheters, always as determined by the treating interventional team. Because embolization is generally intended to be permanent, careful vessel selection and sizing are emphasized so that only the intended territory is occluded.

Transarterial and Targeted Embolization

Transarterial embolization delivers occluding agents through the arterial system to a target territory, and is applied to bleeding, tumors, and other indications. Related targeted approaches such as transarterial radioembolization (TARE) deliver therapy selectively into a tumor's arterial supply through microcatheters. INVAMED's coils, plugs, liquid agent, and delivery catheters are intended to support transarterial occlusion across suitable indications, with the specific combination selected by the operator. Indication, agent choice, and delivery route are all clinical determinations made by the interventional team.

Design and Technical Notes

INVAMED organizes its embolization portfolio around the mechanism of occlusion, offering detachable and pushable coils, a fiber-filled vascular plug, dedicated delivery catheters, a flow-modulating device, and a non-adhesive liquid agent. Each device is intended for use by trained interventionalists under imaging guidance and per the IFU. Catheter and microcatheter compatibility with the chosen coil, plug, or agent is confirmed before delivery to support controlled deployment. All INVAMED embolization devices are intended for use by trained interventionalists under imaging guidance and in accordance with the IFU.

Key Considerations

  • Catheter and microcatheter compatibility with the chosen coil, plug, or agent is confirmed before delivery to support controlled deployment.
  • Detachable designs allow the operator to confirm position before committing, which can be valuable near sensitive branches.
  • Because embolization is usually intended to be permanent, precise vessel selection and sizing are emphasized so that only the intended territory is occluded.

Frequently Asked Questions

Does INVAMED make a liquid embolic agent?

Yes; the Libro Non-Adhesive Embolization Agent is cross-listed in INVAMED's embolization portfolio as a non-adhesive liquid agent, with delivery determined by the operator.

What coils does INVAMED offer?

INVAMED offers the Spider Peripheral Detachable Coil System in detachable and pushable configurations; per invamed.com content surfaced via the search index, the shared Spider coil family uses a platinum-tungsten (92/8%) alloy with roughly 2 to 30 mm coil diameters.

What vessel sizes can the MultiBEAM plug occlude?

According to its product page, the MultiBEAM Embolization Plug is suitable for occlusion of arteries from 2.6 to 6.2 mm, is offered in 4 to 16 mm diameters, and is delivered through a 4F or 5F catheter.

About INVAMED

Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.

Clinical and Technical Context

Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. Whether a flow-modulation strategy is appropriate depends on the lesion and is decided by the operator. Because embolization is generally intended to be permanent, careful vessel selection and sizing are emphasized so that only the intended territory is occluded. INVAMED's Spider Peripheral Detachable Coil System provides detachable and pushable options intended for such peripheral applications.

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Important Disclaimer

This content is educational and technical in nature and must not be interpreted as medical advice or as a promise of any clinical outcome. Individual results depend on many factors and can only be evaluated by a treating physician. Figures attributed to INVAMED reflect manufacturer or published data and are not a guarantee of results. All INVAMED devices are to be used by trained clinicians per the approved IFU, and availability is subject to local regulatory status.

Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

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