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EmbolizationNovember 13, 2006INVAMED Medical Affairs

A Clinical Introduction to Flow-Modulating Devices

How flow modulation embolization works: an educational, technical overview covering the mechanism, applications, considerations, and INVAMED's related…

This article explains, in educational terms, flow modulation embolization — how the technology works and where it fits. Because embolization is generally intended to be permanent, careful vessel selection and sizing are emphasized so that only the intended territory is occluded. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.

Background: Endovascular Embolization

Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. Whether embolization is appropriate, and which agent and delivery system are chosen, is a clinical decision that weighs the target vessel, surrounding anatomy, and overall condition of the patient. Transarterial approaches also include transarterial radioembolization (TARE) and other targeted therapies delivered through dedicated microcatheters, always as determined by the treating interventional team.

Flow-Modulating Devices

Flow-modulating devices are stent-based constructs designed to alter blood flow through a segment rather than to pack a sac directly, and they are used in selected vascular applications. By reorganizing flow, such devices can be used adjunctively in aneurysm and peripheral vascular management as determined by the treating team. INVAMED's Stena Multi-Layer Flow Modulator (Peripheral), also described as the Stena Stent Flow Modulator Embolization Device, is positioned within this category. Whether a flow-modulation strategy is appropriate depends on the lesion and is decided by the operator.

Design and Technical Notes

INVAMED organizes its embolization portfolio around the mechanism of occlusion, offering detachable and pushable coils, a fiber-filled vascular plug, dedicated delivery catheters, a flow-modulating device, and a non-adhesive liquid agent. Each device is intended for use by trained interventionalists under imaging guidance and per the IFU. Matching the embolic agent to the target level of the vascular tree, from proximal plugs and coils to distal particles or liquids, is central to planning. Manufacturer statements about INVAMED devices, including comparative claims on the MultiBEAM product page, reflect the company's positioning rather than guaranteed individual outcomes.

Key Considerations

  • Manufacturer statements about INVAMED devices, including comparative claims on the MultiBEAM product page, reflect the company's positioning rather than guaranteed individual outcomes.
  • Detachable designs allow the operator to confirm position before committing, which can be valuable near sensitive branches.
  • Because embolization is usually intended to be permanent, precise vessel selection and sizing are emphasized so that only the intended territory is occluded.

Frequently Asked Questions

Does INVAMED make a liquid embolic agent?

Yes; the Libro Non-Adhesive Embolization Agent is cross-listed in INVAMED's embolization portfolio as a non-adhesive liquid agent, with delivery determined by the operator.

What vessel sizes can the MultiBEAM plug occlude?

According to its product page, the MultiBEAM Embolization Plug is suitable for occlusion of arteries from 2.6 to 6.2 mm, is offered in 4 to 16 mm diameters, and is delivered through a 4F or 5F catheter.

Is embolization a substitute for surgery?

INVAMED's MultiBEAM product page states the transcatheter plug "provides great benefit instead of surgical treatment in suitable patients" with reportedly high success and low complication rates, but suitability is always a clinical determination.

About INVAMED

Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.

Clinical and Technical Context

Matching the embolic agent to the target level of the vascular tree, from proximal plugs and coils to distal particles or liquids, is central to planning. Whether a flow-modulation strategy is appropriate depends on the lesion and is decided by the operator. INVAMED's coils, plugs, liquid agent, and delivery catheters are intended to support transarterial occlusion across suitable indications, with the specific combination selected by the operator. INVAMED's Spider Peripheral Detachable Coil System offers both detachable and pushable configurations with controlled mechanical detachment; per invamed.com content surfaced via the search index, the shared Spider coil family uses a platinum-tungsten (92/8%) alloy with coil diameters spanning roughly 2 to 30 mm.

Related on INVAMED

Important Disclaimer

The information here is provided for educational purposes and to describe device technology; it is not a substitute for professional medical advice, diagnosis, or treatment. Only a licensed healthcare provider can determine whether a given procedure or device is appropriate for a specific patient. INVAMED products are restricted to use by qualified professionals following the official IFU. Regulatory clearance and labeling differ between regions, and not all products or indications are available in every market.

Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

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