Below is an educational, technical answer to a question many patients and clinicians ask. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Deep Vein Thrombosis (DVT)
Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome. Techniques include mechanical thrombectomy, aspiration thrombectomy, and pharmacomechanical approaches that combine device action with a clot-dissolving drug. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal.
How does mechanical thrombectomy work?
Mechanical thrombectomy works by advancing a catheter to the clot and using suction, rotation, or both to remove it directly from the vein. The goal is to restore venous flow quickly, often in a single session, without depending solely on clot-dissolving drugs. Some systems, such as INVAMED's Mantis PRO, combine rotational disruption with aspiration in one device. The specific technique is chosen by the interventionalist based on clot characteristics.
What This Means in Practice
Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance. Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes. All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU.
Key Considerations
- All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU.
- Large-bore aspiration requires appropriately sized access and attention to blood-loss management.
- Manufacturer performance descriptions reflect device design goals rather than guaranteed individual outcomes.
Frequently Asked Questions
Who is a candidate for catheter-based clot removal?
Candidacy is a clinical decision based on clot extent, location, symptoms, and bleeding risk; this content is educational only.
Is the MultiBEAM IVC filter retrievable?
Yes. INVAMED describes MultiBEAM as a retrievable IVC filter, designed to be removed once the risk of pulmonary embolism has passed.
Can thrombectomy be done in one session?
Mechanical thrombectomy is often designed to restore flow in a single session where feasible, but this depends on the clot and is judged by the operator.
About INVAMED
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Clinical and Technical Context
All INVAMED thrombectomy devices are for use by trained interventionalists under imaging guidance and per the IFU. INVAMED's Mantis CURVE is an over-the-wire rotational pharmacomechanical system, per the company's description. INVAMED's Mantis XP is positioned specifically for fistula thrombectomy. INVAMED's Mantis PRO combines rotational clot disruption with ultra-aspiration in one platform, according to the company. Device choice within a mechanical approach depends on clot location, chronicity, and vessel size. CDT is typically reserved for selected patients after careful bleeding-risk evaluation. Large-bore aspiration requires appropriately sized access and attention to blood-loss management. Effective aspiration depends on matching catheter bore to the target vessel and clot burden. Standard care starts with anticoagulation (blood thinners), but selected patients with large, symptomatic, or limb-threatening clot burden may be considered for catheter-based clot removal. Retrievable IVC filters are intended to be removed once protection is no longer needed, per current guidance. Rotational energy is applied under imaging guidance to protect the vein wall. Endovascular thrombus removal aims to restore venous flow quickly and, in appropriate cases, to reduce the risk of post-thrombotic syndrome.
Related on INVAMED
- Deep Vein Thrombosis (DVT) — product category
- Aspiration thrombectomy vs Rotational thrombectomy: What Is the Difference?
- How is a blood clot removed from the leg?
- IVC Filter Placement: How It Works and Why It Matters
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.