Below is an educational, technical answer to a question many patients and clinicians ask. Acute ischemic stroke from a large vessel occlusion happens when a clot blocks a major brain artery, cutting off blood flow to a region of brain tissue. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Acute Ischemic Stroke and Intracranial Aneurysm Intervention
Because brain tissue is highly time-sensitive, rapid restoration of flow is central to endovascular stroke care in eligible patients. Acute ischemic stroke from a large vessel occlusion happens when a clot blocks a major brain artery, cutting off blood flow to a region of brain tissue. Patient eligibility, the treatment window, and device selection are all determined by the treating neurointerventional team using imaging and current criteria.
How does a liquid embolic agent treat an AVM?
A non-adhesive liquid embolic agent is injected into abnormal vessels, where it precipitates from the outer surface inward as its solvent diffuses into blood, forming a solid cast that occludes the lesion. A radiopaque component allows the operator to visualize the cast under fluoroscopy during injection. INVAMED's Libro agent combines EVOH copolymer, DMSO, and tantalum, and per INVAMED is offered in multiple viscosity formulas for cerebral AVMs and tumors. Agent choice and injection technique are determined by the treating neurointerventionalist.
What This Means in Practice
Manufacturer statements, including the described up-to-24-hour window for the KinG device, reflect product content and do not establish individual eligibility. Liquid embolic use requires attention to concentration, radiopacity, and injection control for the target lesion. For aneurysms, coil sizing and packing or flow-diverter selection are matched to the aneurysm's shape and neck.
Key Considerations
- All INVAMED neurovascular devices are intended for use by trained neurointerventional operators under imaging guidance and per the IFU.
- Speed to reperfusion is a central factor in stroke thrombectomy, which shapes device readiness and workflow in eligible patients.
- Clot characteristics and vessel tortuosity influence whether a stent retriever, aspiration, or combined technique is chosen.
Frequently Asked Questions
What are Spider coils made of?
According to INVAMED, Spider Intracranial Coils are made of a platinum-tungsten 92/8 percent alloy and are offered across 2 to 30 mm coil diameters in detachable and pushable configurations.
Are these neurovascular devices CE marked?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
What is the INVAMED stent retriever called?
INVAMED's stent retriever is the KinG Intracranial Revascularization Device, a self-expanding nitinol device with platinum markers for fluoroscopic visualization.
About INVAMED
INVAMED operates a dedicated R&D center (INVAcenter) focused on minimally invasive device development. INVAMED states it holds more than 100 international patents across its device portfolio.
Clinical and Technical Context
INVAMED's Spider Intracranial Coil System uses a platinum-tungsten 92/8 percent alloy in detachable and pushable configurations with instant mechanical detachment; according to INVAMED, Spider coils provide aneurysm packing across 2 to 30 mm coil diameters. For aneurysms, coil sizing and packing or flow-diverter selection are matched to the aneurysm's shape and neck. Speed to reperfusion is a central factor in stroke thrombectomy, which shapes device readiness and workflow in eligible patients. INVAMED's Mantis Directional Thrombectomy System and AngioHAND Thrombus Removal System are positioned for aspiration-based clot removal in this setting. Liquid embolic use requires attention to concentration, radiopacity, and injection control for the target lesion. INVAMED's Libro Non-Adhesive Embolization Agent combines EVOH copolymer, DMSO solvent, and tantalum powder for radiopacity, and per INVAMED is offered in multiple viscosity formulas, including 6 and 8 percent concentrations, for cerebral AVMs and tumors. Whether a flow diverter is appropriate, versus coiling, is a specialized decision made by the treating clinician. INVAMED's InWIRE Neurovascular Guidewire and neurovascular microcatheters and distal access catheters support this access role.
Related on INVAMED
- Neurovascular Interventions — product category
- Neurovascular Interventions: A Complete Technical Guide
- Liquid Embolic Agents: How It Works and Why It Matters
- What is the first-pass effect in thrombectomy?
Important Disclaimer
This content is educational and technical in nature and must not be interpreted as medical advice or as a promise of any clinical outcome. Individual results depend on many factors and can only be evaluated by a treating physician. Figures attributed to INVAMED reflect manufacturer or published data and are not a guarantee of results. All INVAMED devices are to be used by trained clinicians per the approved IFU, and availability is subject to local regulatory status.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.