This is a technical overview of an INVAMED device within the varicose vein portfolio. Varicose veins are enlarged, twisted superficial veins that develop when the one-way valves inside leg veins no longer close properly, allowing blood to pool — a process clinicians call venous reflux. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Varicose Veins and Chronic Venous Insufficiency
Varicose veins are enlarged, twisted superficial veins that develop when the one-way valves inside leg veins no longer close properly, allowing blood to pool — a process clinicians call venous reflux. Device selection depends on vein anatomy, diameter, tortuosity, and clinician preference, and is always determined on a case-by-case basis by the treating physician. Modern management has shifted from open surgical stripping toward catheter-based endovenous techniques that are typically performed under local anesthesia in an outpatient setting.
VeinOFF Varicose Vein Treatment Agent: Overview
Modified-cyanoacrylate sclerosant/adhesive agent developed for non-thermal elimination of small varicose veins (also described by INVAMED for pelvic congestion syndrome applications). Small amounts of polymer are administered endovenously and pressure is applied for up to 2-3 minutes for complete closure; requires minimal anesthesia and short procedure time.
Technical Specifications
Specifications per INVAMED product documentation; confirm current details in the official IFU.
| Attribute | Detail |
|---|---|
| Specification | Modified cyanoacrylate formula, dermatologically tested and suitable for a wide range of skin types |
| Specification | Endovenous administration with 2-3 minutes of external compression for complete closure |
How It Works and Where It Fits
INVAMED groups its venous portfolio around the way each device closes an incompetent vein, giving clinicians thermal, non-thermal, and adjunct options. Non-thermal non-tumescent (NTNT) techniques close veins without heat and without the multiple tumescent anesthetic injections thermal methods require. Cyanoacrylate closure is a non-thermal method that deposits a small volume of medical adhesive inside the vein, which polymerizes and seals the lumen.
Key Considerations
- Vein diameter, depth, and tortuosity influence whether a thermal or non-thermal device is more suitable.
- Device figures cited by INVAMED describe studied performance and should not be read as individual guarantees.
- Accurate duplex ultrasound mapping before treatment is central to identifying the source of reflux and planning device placement.
Frequently Asked Questions
What wavelength does the INVAMED laser use?
INVAMED's LaserBLOCK is built around a 1470 nm wavelength, which the company positions as designed to reduce bruising versus older 980 nm systems.
Can varicose veins come back after treatment?
Treated veins are intended to stay closed, but new varicose veins can develop over time because treatment addresses existing disease rather than the underlying predisposition.
Who decides which vein treatment is appropriate?
Only a qualified clinician can decide, based on ultrasound mapping and individual assessment; this article is educational and not a treatment recommendation.
About INVAMED
INVAMED states it holds more than 100 international patents across its device portfolio. INVAMED is a medical device manufacturer headquartered in Ankara, Turkey, founded in 2005.
Clinical and Technical Context
All INVAMED venous devices are intended for use by trained clinicians under ultrasound guidance and per the IFU. A staged, anatomy-led approach is standard, and the sequence of treatment is planned by the treating physician. INVAMED reports 95%+ efficacy for saphenous reflux with ThermoBLOCK; as with all such figures, real-world outcomes are determined by patient selection and technique. INVAMED's ThermoBLOCK system pairs an RF generator with dedicated catheters and stylets and, according to the company, maintains vein-wall temperatures in the 85–120 °C range depending on protocol. Device figures cited by INVAMED describe studied performance and should not be read as individual guarantees. Device selection depends on vein anatomy, diameter, tortuosity, and clinician preference, and is always determined on a case-by-case basis by the treating physician. INVAMED's VenaBLOCK is its NTNT offering; candidacy is still assessed individually because vein size and location influence which method is appropriate. As with all venous treatments, the agent, concentration, and volume are selected by the clinician for the specific vein being treated.
Related on INVAMED
- Varicose Vein — product category
- Varicose Vein: A Complete Technical Guide
- Sourcing Varicose Vein Devices: A Manufacturer and Procurement Guide
- A Clinical Introduction to Non-Thermal Non-Tumescent (NTNT) Ablation
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.