The Mantis rotational thrombectomy system is a catheter-based platform engineered by INVAMED for the mechanical disruption and aspiration of thrombus in the peripheral and venous vasculature. This guide outlines the device's design characteristics and intended clinical role for interventionalists evaluating mechanical options for DVT management.
What Is the Mantis Rotational Thrombectomy System?
Mantis is designed around a rotating leaf-shaped tip that engages and fragments thrombus within the treated vessel, paired with an integrated aspiration lumen intended to evacuate fragmented material. The system is intended for mechanical disruption and aspiration of thrombi or emboli in the peripheral and/or venous systems, positioning it as a mechanical option within the broader spectrum of DVT interventions that also includes catheter-directed thrombolysis and pharmacomechanical approaches.
What Are the Key Design Features?
The catheter's construction combines a rotational drive shaft with a flexible outer sheath intended to support navigation through variable venous anatomy:
- Rotating leaf tip — designed to engage thrombus of varying consistency for fragmentation
- Integrated aspiration lumen — intended to remove fragmented clot material during the procedure
- Drive shaft material — constructed from stainless steel or nitinol for rotational transmission
- Outer sheath — a flexible polymer sheath intended to support deliverability through tortuous vascular segments
- Pharmacomechanical compatibility — the platform is designed to support combined mechanical and pharmacologic clot management when clinically indicated
How Does the Rotational Mechanism Work?
During use, the catheter is advanced to the treatment site under fluoroscopic guidance. The rotating leaf tip is activated to mechanically disrupt thrombus, while the aspiration lumen is intended to evacuate fragmented material, reducing the burden of clot that might otherwise be left to embolize or require prolonged pharmacologic dissolution. This dual mechanical-and-aspiration design is intended to give operators flexibility in adapting technique to clot consistency and vessel location.
What Should Clinicians Consider Before Use?
As with any endovascular thrombectomy device, appropriate patient selection, vessel sizing, and procedural technique should follow the official Instructions for Use (IFU). All catheter-based procedures carry inherent risks, including but not limited to vessel injury, bleeding, and incomplete clot removal, and suitability for any individual patient is determined by the treating physician based on a complete clinical assessment.
Frequently Asked Questions
What vessels is the Mantis system intended for?
The Mantis rotational thrombectomy system is intended for mechanical disruption and aspiration of thrombi or emboli within peripheral and/or venous vasculature. Specific indications and sizing should be confirmed against the current IFU.
Can Mantis be used alongside thrombolytic medication?
The platform is designed to support pharmacomechanical use, combining mechanical disruption with localized pharmacologic therapy where clinically appropriate. The decision to combine approaches rests with the treating physician.
What about regulatory status and availability?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Related INVAMED Resources
- Deep Vein Thrombosis (DVT) Product Portfolio
- Comprehensive Catheter & Guidewire Systems
- Request Information from INVAMED
Medical Disclaimer: This article is provided for general informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendation. It is not a substitute for consultation with a qualified healthcare professional. Product indications, availability, and regulatory status vary by country. Always refer to the official Instructions for Use (IFU) and consult a licensed physician for guidance specific to your situation. INVAMED devices are intended for use by trained healthcare professionals.