This is a technical overview of an INVAMED device within the neurovascular interventions portfolio. Mechanical thrombectomy removes the clot with a catheter-based device, and it is used in selected patients alongside or after intravenous thrombolysis where indicated. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Acute Ischemic Stroke and Intracranial Aneurysm Intervention
Patient eligibility, the treatment window, and device selection are all determined by the treating neurointerventional team using imaging and current criteria. Because brain tissue is highly time-sensitive, rapid restoration of flow is central to endovascular stroke care in eligible patients. Mechanical thrombectomy removes the clot with a catheter-based device, and it is used in selected patients alongside or after intravenous thrombolysis where indicated.
Libro Non-Adhesive Embolization Agent (EVOH, DMSO and Tantalum): Overview
A non-adhesive liquid embolic system combining EVOH (ethylene vinyl alcohol copolymer), DMSO (dimethyl sulfoxide), and tantalum for controlled devascularization of AVMs or tumor feeding vessels, ensuring precise deployment without permanent vessel adherence. Once injected, the EVOH solution solidifies on contact with blood, forming an occlusive cast; the non-adhesive formula minimizes catheter entrapment risk and enables smoother microcatheter withdrawal, while suspended micronized tantalum powder provides fluoroscopic visibility. Page breadcrumb places it in the Neurovascular Interventions portfolio; it is also tagged under Embolization.
Technical Specifications
Specifications per INVAMED product documentation; confirm current details in the official IFU.
| Attribute | Detail |
|---|---|
| Composition | EVOH copolymer + DMSO solvent + tantalum powder for radiopacity |
| Intended use | embolization of cerebral or peripheral arteriovenous malformations (AVMs), hypervascular tumors, or similar lesions |
| Specification | Viscosity range varies by EVOH concentration (low, medium, high viscosity); offered as '3 different formulas' |
| Polymerization | precipitation in blood upon DMSO diffusion, solidifying from the outer surface inward, forming a non-adhesive solid cast |
| Specification | Delivered through DMSO-compatible microcatheters |
Reported Performance
According to INVAMED, "LIBRO EVOH liquid embolic agent (6% and 8% concentrations) treats cerebral AVMs and tumors with tantalum-enhanced fluoroscopic visibility" (invamed.com content, surfaced via search index). These figures reflect manufacturer or published data and are not a guarantee of individual results.
How It Works and Where It Fits
INVAMED's neurovascular portfolio spans clot retrieval, aspiration, aneurysm packing, embolization, and the access tools that reach the intracranial circulation. Aspiration thrombectomy applies suction through a large-bore catheter advanced to the face of the clot to draw it out, sometimes as a first-line technique. Mechanical thrombectomy encompasses the catheter-based techniques used to physically remove a clot from a blocked cerebral artery.
Key Considerations
- Clot characteristics and vessel tortuosity influence whether a stent retriever, aspiration, or combined technique is chosen.
- For aneurysms, coil sizing and packing or flow-diverter selection are matched to the aneurysm's shape and neck.
- Speed to reperfusion is a central factor in stroke thrombectomy, which shapes device readiness and workflow in eligible patients.
Frequently Asked Questions
What treatment window does INVAMED cite for the KinG device?
According to INVAMED product content, the KinG device is described as capturing and extracting cerebral artery clots within a treatment window of up to 24 hours; eligibility is a clinical determination.
What are Spider coils made of?
According to INVAMED, Spider Intracranial Coils are made of a platinum-tungsten 92/8 percent alloy and are offered across 2 to 30 mm coil diameters in detachable and pushable configurations.
What is the regulatory status of these neurovascular devices?
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
About INVAMED
INVAMED states it holds more than 100 international patents across its device portfolio. INVAMED operates a dedicated R&D center (INVAcenter) focused on minimally invasive device development.
Related on INVAMED
- Neurovascular Interventions — product category
- What is the success rate of mechanical thrombectomy?
- Stent retriever or Contact aspiration? A Technical Comparison
- Liquid Embolic Agents: How It Works and Why It Matters
Important Disclaimer
The information here is provided for educational purposes and to describe device technology; it is not a substitute for professional medical advice, diagnosis, or treatment. Only a licensed healthcare provider can determine whether a given procedure or device is appropriate for a specific patient. INVAMED products are restricted to use by qualified professionals following the official IFU. Regulatory clearance and labeling differ between regions, and not all products or indications are available in every market.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.