This article explains, in educational terms, liquid embolic agent — how the technology works and where it fits. Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. As a medical device manufacturer, INVAMED develops technologies in this area; the information here is educational and not medical advice.
Background: Endovascular Embolization
Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. Transarterial approaches also include transarterial radioembolization (TARE) and other targeted therapies delivered through dedicated microcatheters, always as determined by the treating interventional team. Whether embolization is appropriate, and which agent and delivery system are chosen, is a clinical decision that weighs the target vessel, surrounding anatomy, and overall condition of the patient.
Liquid Embolic Agents
Liquid embolic agents are injectable materials that solidify within the vessel after delivery, allowing them to penetrate and cast complex networks such as arteriovenous malformations. Non-adhesive agents are designed to precipitate or set without bonding to the catheter tip, which can support more controlled delivery in certain lesions. INVAMED's Libro Non-Adhesive Embolization Agent is cross-listed within the embolization portfolio for such liquid-agent applications. The choice of a liquid agent, its concentration, and the injection technique are determined by the operator based on the lesion architecture.
Design and Technical Notes
INVAMED organizes its embolization portfolio around the mechanism of occlusion, offering detachable and pushable coils, a fiber-filled vascular plug, dedicated delivery catheters, a flow-modulating device, and a non-adhesive liquid agent. Each device is intended for use by trained interventionalists under imaging guidance and per the IFU. Matching the embolic agent to the target level of the vascular tree, from proximal plugs and coils to distal particles or liquids, is central to planning. Catheter and microcatheter compatibility with the chosen coil, plug, or agent is confirmed before delivery to support controlled deployment.
Key Considerations
- Manufacturer statements about INVAMED devices, including comparative claims on the MultiBEAM product page, reflect the company's positioning rather than guaranteed individual outcomes.
- Matching the embolic agent to the target level of the vascular tree, from proximal plugs and coils to distal particles or liquids, is central to planning.
- Catheter and microcatheter compatibility with the chosen coil, plug, or agent is confirmed before delivery to support controlled deployment.
Frequently Asked Questions
What coils does INVAMED offer?
INVAMED offers the Spider Peripheral Detachable Coil System in detachable and pushable configurations; per invamed.com content surfaced via the search index, the shared Spider coil family uses a platinum-tungsten (92/8%) alloy with roughly 2 to 30 mm coil diameters.
Is embolization a substitute for surgery?
INVAMED's MultiBEAM product page states the transcatheter plug "provides great benefit instead of surgical treatment in suitable patients" with reportedly high success and low complication rates, but suitability is always a clinical determination.
What vessel sizes can the MultiBEAM plug occlude?
According to its product page, the MultiBEAM Embolization Plug is suitable for occlusion of arteries from 2.6 to 6.2 mm, is offered in 4 to 16 mm diameters, and is delivered through a 4F or 5F catheter.
About INVAMED
Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.
Clinical and Technical Context
Matching the embolic agent to the target level of the vascular tree, from proximal plugs and coils to distal particles or liquids, is central to planning. According to INVAMED's product page, the MultiBEAM plug applied by transcatheter method "provides great benefit instead of surgical treatment in suitable patients due to its high success, low complication rates and easy applicability," and "the mortality and morbidity rate is lower than the surgical method"; suitability remains a clinical determination. Common applications described in the literature include peripheral aneurysms, arteriovenous fistulas (AVFs) and malformations (AVMs), gastrointestinal or intestinal bleeding, pelvic congestion, varicocele, and endoleaks after aortic repair. INVAMED's MultiBEAM Embolization Plug uses a nitinol framework with possible PTFE or polyester covering, is fiber-filled to promote thrombosis, carries radiopaque platinum markers, and is available in diameters of 4, 6, 8, 10, 12, 14, and 16 mm with an unconstrained length of 7 to 8 mm; according to the product page, it is suitable for occlusion of arteries from 2.6 to 6.2 mm and is delivered through a 4F or 5F catheter with a 0.038 inch inner-diameter lumen advanced through a 5F guide sheath.
Related on INVAMED
- Embolization — product category
- Stena Multi-Layer Flow Modulator (Peripheral) / Stena Stent Flow Modulator Embolization Device: Features, Specifications and Clinical Role
- Pars Detachable Embolization Catheter: Features, Specifications and Clinical Role
- How does a vascular plug differ from a stent?
Important Disclaimer
This article is intended for general educational and technical information about medical device technologies. It is not medical advice, a diagnosis, or a treatment recommendation, and it does not replace consultation with a qualified healthcare professional. Any decision about diagnosis or treatment should be made by a licensed clinician based on an individual assessment. INVAMED devices are intended for use by trained healthcare professionals in accordance with the applicable Instructions for Use (IFU) and local regulatory approvals. Product availability and indications vary by country.
Reviewed by the INVAMED Medical Affairs team. Content is educational and technical in nature.