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Pain Management & Spine (Algology)September 26, 2021INVAMED Medical Affairs

Nerve Ablation Side Effects: Common and Uncommon

An honest look at nerve ablation side effects, from common post-ablation neuritis and numbness to less frequent complications of RFA procedures.

Understanding nerve ablation side effects helps set realistic expectations before undergoing radiofrequency treatment for facet joint or other spine-related pain. Like any medical procedure, radiofrequency ablation carries a range of possible effects, from expected and self-limited sensations to rarer complications that warrant prompt medical attention.

What Side Effects Are Considered Common?

The most frequently reported nerve ablation side effects are localized and temporary. Soreness or bruising at the needle insertion sites is common in the days following the procedure. A temporary flare of pain, meaning symptoms that feel similar to or briefly worse than the patient's baseline pain, is also commonly reported in the first several days before the treatment's intended benefit becomes apparent. Mild swelling and skin sensitivity near the treated area are additionally reported and generally resolve without specific intervention within one to two weeks.

What Is Post-Ablation Neuritis?

Post-ablation neuritis refers to nerve irritation that can occur when the targeted nerve is affected by the radiofrequency energy in a way that produces temporary inflammatory-type symptoms, such as burning, tingling, or increased sensitivity in the distribution of the treated nerve. This is generally described as a self-limited effect, commonly resolving within a few weeks, though the exact duration varies. It is considered a recognized, if less common, side effect distinct from the more typical post-procedural soreness at the injection site.

Is Numbness a Normal Effect of Nerve Ablation?

Because radiofrequency ablation is designed to interrupt sensory nerve signaling, some degree of localized numbness or altered sensation in the skin overlying the treated area can occur, related to the sensory nerve's role in supplying that portion of skin as well as the deeper facet joint. This numbness, when it occurs, is typically limited to a small area and often diminishes as the nerve gradually recovers or regenerates over time. Patients should report any numbness that is widespread, involves motor weakness, or does not improve as expected to their treating physician.

What Uncommon Complications Should Patients Know About?

Less frequently reported complications of radiofrequency ablation include infection at the needle insertion site, bleeding or hematoma formation, and, rarely, injury to structures near the treatment target due to the imaging-guided nature of needle placement. Any signs of infection, such as increasing redness, warmth, swelling, or fever, or any new weakness, loss of bladder or bowel control, or severe unrelenting pain following the procedure should prompt patients to seek immediate medical care, since these can indicate a more serious complication requiring urgent evaluation.

How Are These Risks Communicated Before Treatment?

Before undergoing nerve ablation with a system such as the Peta Radiofrequency Ablation (RFA) System manufactured by INVAMED, patients typically review the procedure's expected effects and potential complications with their treating physician as part of informed consent. A qualified physician determines individual candidacy for the procedure and discusses the relevant risk profile based on the patient's specific anatomy, medical history, and the number of nerve levels planned for treatment. Availability and indications vary by country, and the official Instructions for Use provide complete safety information.

What symptoms after nerve ablation should prompt an urgent call to the doctor?

Signs of infection such as fever, spreading redness, or worsening swelling, along with any new weakness, loss of bladder or bowel control, or severe unrelenting pain, warrant seeking immediate medical care. These are uncommon but recognized red-flag symptoms that differ from the typical, self-limited soreness expected after the procedure.


Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

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