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Ophthalmic & Vision CareApril 28, 2018INVAMED Medical Affairs

Ophthalmic Viscoelastic Devices (OVD): An Overview

Ophthalmic viscoelastic devices (OVD) overview: role in cataract and anterior segment surgery, general categories, and handling considerations.

An ophthalmic viscoelastic device, commonly abbreviated OVD, is a gel-like substance used during anterior segment eye surgery, most notably cataract surgery, to maintain space within the eye and protect delicate intraocular tissues. This overview reviews the general role, categories, and handling considerations relevant to OVD use for a healthcare professional audience.

What General Role Does an OVD Play During Surgery?

During procedures such as phacoemulsification, an OVD is injected into the anterior chamber to maintain chamber depth and stability after the natural aqueous fluid is displaced through the surgical incision. This space-maintaining function is intended to create a protected working environment, helping shield sensitive structures — most notably the corneal endothelium — from mechanical trauma or turbulence caused by instruments and fluid movement during the procedure.

What General Categories of OVDs Exist?

OVDs are generally classified into a few broad categories based on their rheological (flow) properties:

  • Cohesive OVDs: Tend to maintain their shape as a single mass and are generally associated with good space maintenance, and are typically removed from the eye more readily as a unit at the end of the case.
  • Dispersive OVDs: Tend to coat and adhere to tissue surfaces, which is generally associated with enhanced tissue-coating protection, particularly for the corneal endothelium, though they may be more difficult to fully remove.
  • Viscoadaptive/combination OVDs: Designed to combine characteristics of both categories depending on the surgical step.

Selection among these general categories, or use of more than one during a single case (a technique sometimes called the "soft-shell" approach), is determined by the operating surgeon based on the specific surgical step and patient anatomy.

What Handling Considerations Are Relevant to OVD Use?

Clinicians and surgical staff generally consider several factors when working with OVDs, including proper injection technique to avoid overfilling the anterior chamber, awareness of the specific product's viscosity and cohesive or dispersive behavior, and thorough removal at the end of the case, since residual OVD left in the eye has been associated with postoperative intraocular pressure elevation in some cases. Facility-specific protocols and the product's IFU should guide handling, storage, and use.

Why Does OVD Selection Matter for Surgical Outcomes?

Appropriate OVD selection is generally considered relevant to reducing intraoperative complications such as corneal endothelial cell trauma and to supporting a stable surgical environment throughout the case. As with any surgical adjunct, OVD use carries general risks and limitations, and outcomes depend on proper technique, appropriate product selection for the surgical step, and individual patient factors. Clinicians should refer to the applicable product IFU for specific handling, injection, and removal guidance.

Frequently Asked Questions

Are all OVDs interchangeable during a case?

No. Cohesive and dispersive OVDs have different handling characteristics and are generally selected for specific surgical steps based on the properties needed at that point in the procedure, such as space maintenance versus tissue coating.

Why is thorough OVD removal important at the end of surgery?

Residual viscoelastic material left in the eye has been associated with transient postoperative intraocular pressure elevation in some cases, which is one reason thorough removal is generally emphasized as part of standard technique.

Is OVD use limited to cataract surgery?

While OVDs are most commonly discussed in the context of cataract surgery, they are also used more broadly across various anterior segment ophthalmic procedures where space maintenance and tissue protection are relevant.

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Medical Disclaimer: This article is provided for general informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendation. It is not a substitute for consultation with a qualified healthcare professional. Product indications, availability, and regulatory status vary by country. Always refer to the official Instructions for Use (IFU) and consult a licensed physician for guidance specific to your situation. INVAMED devices are intended for use by trained healthcare professionals.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

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