Wide-necked bifurcation aneurysms are among the most technically demanding lesions to treat endovascularly. Intrasaccular flow disruption addresses them with a single, self-expanding mesh device deployed inside the aneurysm sac, positioned to disrupt blood flow across the neck and induce thrombosis without the need for a separate parent-vessel stent in many cases.
Principle of action
The device forms a barrier at the aneurysm neck that reduces and redirects inflow, promoting stasis and progressive thrombosis within the sac. Because the construct sits within the aneurysm rather than the parent artery, dual antiplatelet therapy requirements are typically reduced compared with parent-vessel devices — an advantage in ruptured presentations.
Technical considerations
- Accurate sizing to the aneurysm width and height is critical for stable seating and neck coverage.
- Stable microcatheter position supports controlled deployment in a bifurcation.
- Assessment of neck and dome geometry determines candidacy; irregular or very small aneurysms require careful judgment.
- Retrievability before detachment allows repositioning if seating is suboptimal.
Clinical outcomes
Published series describe favorable rates of adequate occlusion at follow-up for appropriately selected bifurcation aneurysms, with occlusion often improving over time. The single-device workflow can shorten procedures and reduce hardware in the parent vessel. As with all aneurysm therapies, durable results depend on case selection, accurate sizing, and imaging follow-up.
INVAMED technologies in this space
INVAMED's neurovascular portfolio includes access, navigation, and aneurysm-treatment devices; explore the neurovascular interventions category.
Device availability and approved indications vary by country. This content is prepared for healthcare professionals and does not replace clinical judgment or the instructions for use.