Minimally invasive medicine advances one engineering breakthrough at a time. At INVAcenter — the INVAMED research and development hub in Ankara — more than 40 biomedical engineers work alongside clinicians to translate unmet procedural needs into practical technologies, protected by a portfolio of over 100 international patents filed across six continents.
Technology platforms
Flow modulation
The STENA Multilayer Flow Modulator represents a distinct approach to complex aortic and peripheral aneurysms: a three-dimensional braided multilayer construct that redirects flow toward laminar patterns and promotes sac thrombosis while preserving perfusion through branch vessels — an engineering answer to one of endovascular therapy's most persistent trade-offs.
Non-thermal venous closure
The VenaBlock cyanoacrylate platform closes incompetent superficial veins without tumescent anesthesia or thermal energy, supported by peer-reviewed comparative data and registry outcomes. See our Clinical Evidence page for published studies.
Mechanical thrombectomy
The Mantis family spans rotational, aspiration, and pharmacomechanical clot removal, engineered for single-session treatment of deep venous and arterial thrombosis. The VascuVac program extends this work with sensing-assisted aspiration control.
Orthopedic fixation systems
The CytroFIX ecosystem — intramedullary nails, anatomically contoured locking plates, and a magnetic limb-lengthening nail — reflects a design philosophy of anatomic fit, biological respect for the soft-tissue envelope, and early mobilization.
How we innovate
- Clinician-first design: development begins in the procedure room, with physician-identified friction points shaping every specification.
- Rapid iteration: in-house prototyping, bench testing, and simulation shorten the path from concept to clinical evaluation.
- Evidence generation: registries, comparative studies, and post-market surveillance close the loop between design intent and real-world performance.
- Cross-disciplinary depth: expertise spanning cardiovascular biomechanics, polymer science, nitinol processing, and embedded systems under one campus roof.
Research collaboration
INVAcenter partners with universities, teaching hospitals, and independent investigators on device development, registry participation, and translational research. Institutions interested in collaboration can reach our team through the contact page.
Explore the technologies born from this work across our product portfolio, or review the published clinical evidence behind them.