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Ophthalmic & Vision CareAugust 20, 2022INVAMED Medical Affairs

Vitrectomy Basics: Surgery Inside the Eye

An introduction to vitrectomy surgery, covering pars plana vitrectomy technique, gas bubble use, and small-gauge instrument systems.

Vitrectomy is a surgical procedure that removes the vitreous, the clear gel that fills the back cavity of the eye, to gain access to the retina for treatment of a range of conditions. Because the retina sits at the very back of the eye behind this gel, vitrectomy has become an essential technique whenever a condition requires direct surgical access to retinal tissue rather than treatment through the pupil alone.

Why Would Someone Need Vitrectomy?

Vitrectomy is performed for a variety of reasons, including retinal detachment, vitreous hemorrhage (bleeding into the eye, often related to diabetic retinopathy), macular holes, epiretinal membranes that distort central vision, severe eye infections, and complications from prior eye surgery. In each of these situations, the vitreous gel itself may be contributing to the problem, through traction on the retina or by clouding vision with blood, or it may simply be in the way of the surgeon accessing and treating the retina directly.

What Happens During Pars Plana Vitrectomy?

Pars plana vitrectomy is the standard modern technique, named for the pars plana, a safe entry zone near the front of the eye that avoids the retina and lens. The surgeon creates several tiny incisions, or ports, through which specialized instruments are inserted: an infusion line to maintain the eye's shape and pressure, a light source to illuminate the interior, and a cutting or aspiration instrument to remove the vitreous gel. Once the vitreous is removed, the surgeon can address the underlying condition directly, which might include peeling a membrane, repairing a macular hole, or applying laser to seal retinal tears using an endolaser probe.

What Role Does a Gas Bubble Play?

At the end of many vitrectomy procedures, the surgeon may fill the eye with a gas bubble in place of the removed vitreous gel. This bubble acts as an internal, temporary support that presses gently against the retina from the inside, helping to hold it in place while healing occurs, particularly after retinal detachment repair or macular hole surgery. Patients are often asked to maintain a specific head position for some days after surgery to keep the bubble positioned correctly over the treated area. The gas bubble gradually resorbs over one to several weeks, depending on the type of gas used, and is eventually replaced by the eye's own natural fluid.

What Does Small-Gauge Surgery Mean?

Modern vitrectomy is often performed using small gauge surgery, referring to very fine instruments, commonly in the 23, 25, or 27 gauge range, that allow the procedure to be done through incisions small enough to often be self-sealing, without the need for sutures. This has generally been associated with faster postoperative comfort and quicker visual recovery compared with older, larger-gauge instrumentation, though the appropriate gauge for a given case depends on the surgical goal and the surgeon's assessment. Endolaser probes used during vitrectomy, such as the Horus Optic Laser Probes manufactured by INVAMED, are available in 20, 23, 25, and 27 gauge configurations as stated by the manufacturer, reflecting this range of small-gauge surgical approaches. More information on this device is available on the INVAMED product page for the Horus Optic Laser Probes.

What Should Patients Expect After Vitrectomy?

Recovery after vitrectomy varies depending on the underlying condition treated and whether a gas bubble was used. Patients commonly experience blurred vision in the initial period, especially if a gas bubble is present, along with mild discomfort and light sensitivity. A qualified ophthalmologist provides specific postoperative instructions, including any positioning requirements, and determines the surgical approach best suited to each patient's condition, since vitrectomy technique and goals differ considerably across the range of conditions it treats.

Is vitrectomy considered a major or minor surgery?

Vitrectomy is a genuine surgical procedure performed in an operating room, typically under local or general anesthesia, but it is often done on an outpatient basis with small, frequently self-sealing incisions. Its complexity and recovery expectations depend heavily on the underlying condition being treated.


Device availability and regulatory status vary by country. Please contact INVAMED or your authorized local distributor for current regulatory information applicable to your region.

Reviewed by: INVAMED Medical Affairs

This content is prepared for educational purposes for healthcare professionals and does not constitute medical advice. Always consult clinical guidelines and product instructions for use.

vitrectomypars plana vitrectomygas bubblesmall gauge surgeryophthalmologyvitreoretinal surgeryretina
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