的 HyperTiss Intracavitary Hypothermia Set offers a multifactorial approach to bladder tumor management by combining chemotherapy with targeted hyperthermia in a controlled, patient-friendly delivery system. Through a specialized Three-Way Foley Silicone Catheter and advanced temperature control technology, HyperTiss ensures precise thermal and drug regulation—optimizing chemo-hyperthermia’s efficacy against cancerous tissue within the bladder while prioritizing patient safety and comfort.
System Components & Design
Three-Way Foley Silicone Catheter
- High-Quality Silicone: Minimizes irritation to the bladder wall, promoting patient tolerance during extended intravesical therapy.
- Multi-Port Access: Enables drug instillation, temperature monitoring, and continuous fluid exchange with minimal instrumentation.
Connection Connectors & Two-Way Stopcock
- Secure Fluid Pathways: Prevents leakage or accidental disconnection, providing stable infusion and drainage ports for the anticancer solution.
- Two-Way Stopcock: Offers operator-friendly toggling between infusion, drainage, or sealed modes during the procedure.
Heat Probe
- Precise Temperature Regulation: Monitors and maintains fluid temperature within a 41–44°C range (±0.2°C) per physician protocol.
- Optimized Hyperthermia Delivery: Ensures uniform heat distribution across the bladder mucosa, enhancing drug uptake.
Clamp, Medical Grade PVC Tubing & Bag
- Fluid Management: Simplifies infusion, drainage, or recirculation processes for delivering heated chemotherapy solutions.
- Transparent & Latex-Free: Allows clinicians to observe fluid levels and flow conditions, supporting safe handling.
矽膠套管
- Flexible, Atraumatic: Minimizes mechanical stress on the bladder or the infusion line, enhancing patient safety and comfort.
- Biocompatible Construction: Resists kinking and maintains consistent fluid passage even under repeated bending.
Therapeutic Rationale: Chemo-Hyperthermia
Synchronized Temperature & Drug Delivery
- HypertISS: (Hypothermia might be a mis-labelling or it’s “HyperTiss” but anyway) By raising local tissue temperature to 41–44°C, the synergy between heat and chemotherapeutic solutions intensifies cancer cell death.
- Favorable Tissue Response: Hyperthermia triggers changes in tumor vasculature, enhancing chemotherapeutic penetration and susceptibility of malignant cells to cytotoxic agents.
Reduced Recurrence Rates
- Improved Oncologic Control: Enhanced tissue drug levels plus disruption of tumor cell defense mechanisms can lower progression or relapse of bladder tumors.
- Better Resource Allocation: Effective local therapy can lessen the need for extensive systemic treatments, cutting down cost and toxicity profiles.
臨床優點與適應症
Enhancing Chemotherapy Efficacy
- Targeted Hyperthermia: Elevates local temperature in the bladder to potentiate chemotherapeutic effects, thereby improving tumor cell kill rates.
- Increased Drug Penetration: Heated environment encourages deeper and more consistent uptake of anticancer agents.
Multifactorial Mode of Action
- Combination of Heat & Ionized Molecule Delivery: Creates a synergy that overcomes drug resistance and fosters thorough coverage of bladder lesions.
- Reduced Systemic Toxicity: Local administration confines drug exposure mainly to the bladder region, potentially lowering systemic side effects.
User-Friendly & Patient-Centric
- Outpatient/Local Anesthesia: Many procedures can be performed on a short-stay basis, optimizing hospital resources and improving patient quality of life.
- Reliable Monitoring & Control: Comprehensive alarm systems plus real-time temperature feedback maintain high standards of safety.
Robust Safety Measures
- Automatic Safety Shutdown: Mitigates risk if unexpected temperature or pressure fluctuations occur.
- Alarm Alerts: Minimizes operator error and ensures the procedure remains within the safe therapeutic window.
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